Testosterone supplements, such as the prescription topical treatments Androgel, Testim and Axiron, are used to help boost testosterone levels in men who have a deficiency of the male hormone. Low testosterone symptoms include decreased libido and low energy. It has been estimated that up to 13 million men older than 45 years of age in the U.S. may have symptoms associated with low testosterone.
Testosterone deficiency is a clinical condition in which the testicles, hypothalamus or pituitary gland is affected by disease or damage that results in inhibiting hormone secretion and testosterone production.
AndroGel 1% and AndroGel 1.62% are both prescription products used for daily testosterone replacement therapy (TRT). They are manufactured by Abbott Laboratories. The gel is applied to the skin of the shoulders and upper arms. AndroGel 1% may also be applied to the abdomen. The area where the gel was applied should be covered, and patients are warned that others should not come into contact with the skin where the gel was applied.
AndroGel 1% was approved by the FDA in February 2000. In 2007, 1.4 million prescriptions for AndroGel 1% – the most commonly dispensed gel form of testosterone – were dispensed by U.S. retail pharmacies. Approximately 25,000 of those were dispensed for off-label use in women.
Testim is a prescription medicine that contains testosterone. It is used to treat adult males who have low testosterone (also commonly called low-T) or no testosterone. It is a gel that is applied to the skin of the shoulders and upper arms. The area where the gel is applied should be covered, and patients are warned that others should not come into contact with the skin where the gel was applied. Testim is manufactured for Auxilium Pharmaceuticals, Inc., by DPT Laboratories, Ltd.
Testim 1% was approved by the FDA in October 2002. There were approximately 400,000 prescriptions dispensed for Testim 1% in 2008.
Axiron is a prescription medication that contains testosterone and is used to treat low testosterone (low-T) or no testosterone in adult men. It is the only underarm low testosterone treatment. Axiron is manufactured and distributed by Eli Lilly and Company and Acrux. It was approved by the FDA in November 2010 and had sales of $48 million in 2011.
Axiron is the first testosterone topical solution approved for application via an armpit (underarm) applicator. The recommended starting dose is 60 mg applied once a day, preferably at the same time each morning. Axiron can transfer from the body to others. This can happen if other people come into contact with the area where Axiron was applied. The area where the product was applied should be covered, and patients are warned that others should not come into contact with the skin where Axiron was applied.